Linked Life Data

1487756

Source:http://linkedlifedata.com/resource/pubmed/id/1487756

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-2-24
pubmed:abstractText
HIV-1 seropositive patients have a high frequency of nervous system diseases, and asymptomatic abnormalities are frequently detected. We studied 124 neurologically asymptomatic HIV-1 seropositive subjects and 23 normal control subjects by nerve conduction studies. No alterations were detectable in the asymptomatic stages of infection (CDC groups II and III), while subclinical peripheral nervous system (PNS) impairment was detected in symptomatic HIV-1 stages (CDC group IV). Specifically, in CDC group IV we observed a reduction in the motor conduction velocity of the deep peroneal nerve and the median nerve, and a similar reduction of the sensory conduction velocity of the sural nerve. There were no differences of the amplitude and area of the muscular response or of the sensory nerve action potential. As our patients did not present clinical or laboratory evidence for a toxic-dismetabolic etiology, our data indicate a progressive myelin damage more directly related to HIV-1 infection. This subclinical finding may have importance for the progression of the disease in the PNS.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0022-510X
pubmed:author
pubmed:issnType
Print
pubmed:volume
113
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
209-13
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Electrophysiologic study of HIV-1 + patients without signs of peripheral neuropathy.
pubmed:affiliation
Department of Neurological and Psychiatric Sciences, University of Florence, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't