Source:http://linkedlifedata.com/resource/pubmed/id/14872482
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-2-11
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pubmed:abstractText |
The strongest known genetic association in rheumatoid arthritis (RA) is with HLA-DRB1 alleles that share a similar amino acid sequence, termed the shared epitope (SE). Although many studies have examined the association of the SE with disease severity, the results have been inconsistent, which may reflect the relatively small sample sizes or ethnic differences. The aim of this study was to assess the association of HLA-DRB1 SE alleles and genotype with the development of bony erosions in RA by meta-analysis.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0004-3591
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
400-12
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:14872482-Arthritis, Rheumatoid,
pubmed-meshheading:14872482-Epitopes,
pubmed-meshheading:14872482-Female,
pubmed-meshheading:14872482-Genetic Predisposition to Disease,
pubmed-meshheading:14872482-Genotype,
pubmed-meshheading:14872482-HLA-DR Antigens,
pubmed-meshheading:14872482-HLA-DRB1 Chains,
pubmed-meshheading:14872482-Histocompatibility Testing,
pubmed-meshheading:14872482-Humans,
pubmed-meshheading:14872482-Male,
pubmed-meshheading:14872482-Population Groups
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pubmed:year |
2004
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pubmed:articleTitle |
Impact of shared epitope genotype and ethnicity on erosive disease: a meta-analysis of 3,240 rheumatoid arthritis patients.
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pubmed:affiliation |
University of California, San Francisco, CA 94143-0500, USA. lac@itsa.ucsf.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Meta-Analysis
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