Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1993-2-22
pubmed:abstractText
A case of Kimura's disease affecting the eyelids bilaterally is reported in a 5-year-old boy of Afro-Caribbean extraction who has been followed for 12 years with repeat biopsies. He initially presented at 5 years of age with swelling of the left upper eyelid, left cervical lymphadenopathy, and eosinophilia. One year later he developed swelling of the right upper eyelid. There has been no change in the clinical appearance over the next 12 years. Repeated biopsies of the eyelids showed a diffuse inflammatory infiltrate with many eosinophils and lymphocytes. A lymph node biopsy showed reactive lymphoid hyperplasia. Immunohistochemistry using lymphoid markers showed a polyclonal pattern. Kimura's disease is a rare cause of eyelid swelling, particularly at such a young age and with bilateral involvement. This case demonstrates that bilateral orbital lymphoid lesions with cervical node involvement do not always imply lymphoma, but may have a benign pathogenesis. The unusually long follow up in this case confirms an excellent prognosis for Kimura's disease with conservative management. Accurate diagnosis in small orbital biopsies may spare the patient unnecessary radical surgery.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-13878112, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-2461103, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-2606453, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-2658631, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-2919716, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-3154745, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-3370008, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-3428821, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-489888, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-527967, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-6166661, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-6410919, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-6718071, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-7042523, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-7136553, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-7248721, http://linkedlifedata.com/resource/pubmed/commentcorrection/1486082-765004
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0007-1161
pubmed:author
pubmed:issnType
Print
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
755-7
pubmed:dateRevised
2010-9-7
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Bilateral Kimura's disease of the eyelids.
pubmed:affiliation
Tennent Institute of Ophthalmology, Western Infirmary, Glasgow.
pubmed:publicationType
Journal Article, Case Reports