Linked Life Data

1484879

Source:http://linkedlifedata.com/resource/pubmed/id/1484879

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1993-2-17
pubmed:abstractText
The immediate metabolic, cationic, and secretory response of the insulin-producing B-cell to D-glucose is regulated, in a delayed or long-term manner, by nutritional factors such as food availability, feeding schedule, or diet composition. The B-cell keeps the memory of these nutritional manipulations so that the corresponding changes in its responsiveness to D-glucose can be documented in vitro in isolated pancreatic islets. The results of experiments conducted in starved rats, in animals exposed to an altered feeding schedule, and in rats given free access to a high-carbohydrate, high-protein, or high-lipid, as distinct from balanced, diet all suggest that a sufficient prandial hyperglycemia is essential for maintenance of an optimal metabolic and secretory behavior of the islet B-cell in response to a rise in D-glucose concentration.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0031-9384
pubmed:author
pubmed:issnType
Print
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1193-6
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Long-term regulation of pancreatic B-cell responsiveness to D-glucose by food availability, feeding schedule, and diet composition.
pubmed:affiliation
Department of Physiology and Biophysics, University of Sao Paulo, Brazil.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't