Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1993-2-18
pubmed:abstractText
Noradrenaline depletion of the olfactory bulbs induces cannibalism at parturition in primiparous mice, without producing anosmia or impairment of maternal behaviour. Similar lesions made in multiparous experienced females do not result in cannibalism. The present studies investigated 1) whether a 30-min exposure to pups or to distal cues from pups given to virgin females before noradrenaline depletion of the olfactory bulbs overcame the impairment in recognition at first parturition, and 2) whether noradrenaline-depleted females allowed to care for their pups for the 24 h following parturition showed a failure in recognition on a second parturition. Experiment 1 showed that exposure to distal cues from pups enabled the females to successfully recognize pups at parturition in comparison to naive females. However, neither the exposure to pup cues nor the fully interactive experience with pups overcame the disruptive effect on recognition at birth of the noradrenaline depletion. In Experiment 2, we found that olfactory recognition was impaired in noradrenaline-depleted females on second parturition, in spite of the mothering experience with their own pups.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0031-9384
pubmed:author
pubmed:issnType
Print
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
901-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Olfactory recognition of infants in laboratory mice: role of noradrenergic mechanisms.
pubmed:affiliation
Laboratorio di Fisiopatologia di Organo e di Sistema, Istituto Superiore di Sanità, Roma, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't