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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1993-2-18
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pubmed:abstractText |
Eighty cases of cystectomized and step-sectioned pT1 transitional cell carcinomas of various grades were analyzed. During the same period, 30 consecutive cases of pT2 carcinomas were also cystectomized and examined for comparison. This is a cross-sectional study of a variety of cases of bladder cancer, designed to delineate the characteristics of G3.pT1 disease. Tumors in this series had a full set of various pathological findings; grades 1 to 3, stages Ta-T1-T2, papillary-papillonodular-nodular tumor configuration, alpha-beta-gamma type of invasion, presence of lymphatic and venous involvement, and presence of associated carcinoma in situ/dysplasia. There is a distinct tendency of stepwise disease progression, such as grade 1-->3, stage T1-->T2, papillary-->nodular configuration, and alpha-->gamma invasion, these factors being mutually related. We noted a similarity between tumor groups containing G3 component, such as G2-3.pT1, G3 > 2.pT1, G3.pT1, G1-3.pT2, and G3.pT2. These tumors are different from groups such as G1-2.pT1, G2.pT1 and G2 > 3.pT1 in terms of tumor configuration and type of invasion. As regards pT1 having G3 components, early cystectomy seems to be the surest treatment. Whenever one adopts a conservative policy in treatment of these tumors, extreme care should be taken to monitor tumor progression.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0910-5050
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
83
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1354-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1483949-Adult,
pubmed-meshheading:1483949-Aged,
pubmed-meshheading:1483949-Aged, 80 and over,
pubmed-meshheading:1483949-Carcinoma, Transitional Cell,
pubmed-meshheading:1483949-Cystectomy,
pubmed-meshheading:1483949-Female,
pubmed-meshheading:1483949-Humans,
pubmed-meshheading:1483949-Male,
pubmed-meshheading:1483949-Middle Aged,
pubmed-meshheading:1483949-Neoplasm Invasiveness,
pubmed-meshheading:1483949-Neoplasm Metastasis,
pubmed-meshheading:1483949-Neoplasm Staging,
pubmed-meshheading:1483949-Urinary Bladder Neoplasms
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pubmed:year |
1992
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pubmed:articleTitle |
Analysis by step sectioning of early invasive bladder cancer with special reference to G3.pT1 disease.
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pubmed:affiliation |
Urology Division, National Cancer Center Hospital, Tokyo.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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