Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1993-2-12
|
| pubmed:abstractText |
This report describes the safety and efficacy of the procedure for percutaneous injection of medical-grade polyurethane elastomer (MPU) to form plugs in the vas deferens. The injection of 0.16-0.22 ml MPU in 53 men resulted in occlusion and azoospermia in 85% of the men after 12 months; 96% achieved azoospermia by 2 years. The success rate of the method and the rate of sperm suppression to azoospermia depended on the shapes of the plugs; this was determined by palpation after insertion. There were few complications and the results are discussed in terms of the reversibility potential of this method.
|
| pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/Asia,
http://linkedlifedata.com/resource/pubmed/keyword/CHINA,
http://linkedlifedata.com/resource/pubmed/keyword/Clinical Research,
http://linkedlifedata.com/resource/pubmed/keyword/Clinical Trials,
http://linkedlifedata.com/resource/pubmed/keyword/Developing Countries,
http://linkedlifedata.com/resource/pubmed/keyword/Eastern Asia,
http://linkedlifedata.com/resource/pubmed/keyword/Equipment And Supplies,
http://linkedlifedata.com/resource/pubmed/keyword/Examinations And Diagnoses,
http://linkedlifedata.com/resource/pubmed/keyword/Family Planning,
http://linkedlifedata.com/resource/pubmed/keyword/Ingredients And Chemicals,
http://linkedlifedata.com/resource/pubmed/keyword/Laboratory Examinations And Diagnoses,
http://linkedlifedata.com/resource/pubmed/keyword/Laboratory Procedures,
http://linkedlifedata.com/resource/pubmed/keyword/Male Sterilization,
http://linkedlifedata.com/resource/pubmed/keyword/POLYMERS,
http://linkedlifedata.com/resource/pubmed/keyword/Plugs,
http://linkedlifedata.com/resource/pubmed/keyword/Prospective Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology,
http://linkedlifedata.com/resource/pubmed/keyword/Research Report,
http://linkedlifedata.com/resource/pubmed/keyword/Sperm Count,
http://linkedlifedata.com/resource/pubmed/keyword/Sterilization, Sexual,
http://linkedlifedata.com/resource/pubmed/keyword/Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Surgical Equipment,
http://linkedlifedata.com/resource/pubmed/keyword/Vas Occlusion,
http://linkedlifedata.com/resource/pubmed/keyword/Vasectomy
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0105-6263
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
468-72
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:otherAbstract |
PIP: In China, physicians performed percutaneous injection of medical-grade polyurethane (MPU) in 53 men at the National Research Institute for Family Planning in Beijing and followed them for 2 years to evaluate the safety and efficacy of MPU vas occlusion. The injection of 1% procaine solution was used to kill residual spermatozoa in the distal reproductive tract. 1 year and within-subject fructose levels did not fluctuate greatly. 85% of the men reached azoospermia within 1 year after vas occlusion. 96% were azoospermic at 18 months. 2 men still had spermatozoa in the semen after 2 years (8-48 million ml-1). Both MPU plugs in most men (74%) had a regular shape. All of these men reached azoospermia by 18 months. 91% of the 11 men who had 1 regular and 1 irregular shaped MPU plug reached azoospermia by 18 months. This percentage fell to 67% for the 3 men whose MPU plugs were both irregular. The physicians had removed irregularly shaped MPU plugs in 5 men earlier and the elastomer filled the vas lumen and the surrounding vas surface. Recanalization did not occur in these 5 patients. 1 man with MPU vas occlusion developed a hematoma. 3 men experienced hemaspermia within 2 weeks after vas occlusion, but medication made it disappear within 4 weeks. Injection of 1% procaine solution may have damaged the seminal vesicles, resulting in the hemaspermia. Longterm complications did not occur.
|
| pubmed:meshHeading |
pubmed-meshheading:1483736-Adult,
pubmed-meshheading:1483736-Follow-Up Studies,
pubmed-meshheading:1483736-Humans,
pubmed-meshheading:1483736-Injections,
pubmed-meshheading:1483736-Male,
pubmed-meshheading:1483736-Polyurethanes,
pubmed-meshheading:1483736-Prostheses and Implants,
pubmed-meshheading:1483736-Safety,
pubmed-meshheading:1483736-Sterilization, Reproductive,
pubmed-meshheading:1483736-Vas Deferens
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
Safety and efficacy of percutaneous injection of polyurethane elastomer (MPU) plugs for vas occlusion in man.
|
| pubmed:affiliation |
National Research Institute for Family Planning, Beijing, China.
|
| pubmed:publicationType |
Journal Article
|