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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1993-2-17
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pubmed:abstractText |
The sera of 122 patients with uveitis were examined for the presence of various antinuclear autoantibodies. Overall 21.3% of the patients had antibodies to ribonucleoprotein (RNP) and 18% to Ro (SSA). When subdividing the patients according to primary uveitis versus secondary uveitis, the autoantibodies were detected more frequently in the second group [anti-RNP 13.3 vs. 31.4%, anti-Ro (SSA) 11.8 vs. 27.7%, anti-Sm 10.3 vs. 24% and poly (G) 2.9 vs. 14.8%, respectively]. No differences could be asserted in autoantibody frequencies according to disease location within the uvea. Among uveitis patients afflicted with sarcoidosis a particular high incidence of autoantibodies was detected in comparison with all other subgroups of patients with uveitis. Although the presence of autoantibodies among patients with uveitis appears not to have a major diagnostic value, their assessment may aid to a better understanding of disease pathogenesis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1018-2438
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
99
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
34-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1483065-Antibodies, Antinuclear,
pubmed-meshheading:1483065-Autoantibodies,
pubmed-meshheading:1483065-Behcet Syndrome,
pubmed-meshheading:1483065-DNA,
pubmed-meshheading:1483065-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:1483065-Humans,
pubmed-meshheading:1483065-Incidence,
pubmed-meshheading:1483065-Lupus Erythematosus, Systemic,
pubmed-meshheading:1483065-Sarcoidosis,
pubmed-meshheading:1483065-Uveitis, Anterior,
pubmed-meshheading:1483065-Uveitis, Posterior
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pubmed:year |
1992
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pubmed:articleTitle |
Analysis of autoantibodies among patients with primary and secondary uveitis: high incidence in patients with sarcoidosis.
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pubmed:affiliation |
Research Unit of Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer affiliated to Tel-Aviv University Medical School Israel.
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pubmed:publicationType |
Journal Article
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