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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1993-2-8
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pubmed:abstractText |
In this study the identity of annexins in human platelets has been determined together with their ability to be released by agents which induce platelet degranulation. The presence of proteins cross-reacting to antibodies against annexins I and V was detected in human platelets. However, the study provided evidence that these annexins are not located on the surface of the plasma membrane in a Ca++ dependent manner. Moreover, activation of platelets with several agents which induced platelet degranulation did not cause release of annexins I or V as determined by both immunoblotting and ELISA.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Annexin A1,
http://linkedlifedata.com/resource/pubmed/chemical/Annexin A2,
http://linkedlifedata.com/resource/pubmed/chemical/Annexin A4,
http://linkedlifedata.com/resource/pubmed/chemical/Annexin A5,
http://linkedlifedata.com/resource/pubmed/chemical/Annexins,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Edetic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Egtazic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Ionomycin,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet Activating Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Serotonin,
http://linkedlifedata.com/resource/pubmed/chemical/Tetradecanoylphorbol Acetate,
http://linkedlifedata.com/resource/pubmed/chemical/Thrombin
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0006-291X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
189
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1739-46
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1482379-Annexin A1,
pubmed-meshheading:1482379-Annexin A2,
pubmed-meshheading:1482379-Annexin A4,
pubmed-meshheading:1482379-Annexin A5,
pubmed-meshheading:1482379-Annexins,
pubmed-meshheading:1482379-Antibodies,
pubmed-meshheading:1482379-Blood Platelets,
pubmed-meshheading:1482379-Blotting, Western,
pubmed-meshheading:1482379-Cross Reactions,
pubmed-meshheading:1482379-Cytoplasmic Granules,
pubmed-meshheading:1482379-Edetic Acid,
pubmed-meshheading:1482379-Egtazic Acid,
pubmed-meshheading:1482379-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:1482379-Humans,
pubmed-meshheading:1482379-Ionomycin,
pubmed-meshheading:1482379-Kinetics,
pubmed-meshheading:1482379-Platelet Activating Factor,
pubmed-meshheading:1482379-Platelet Activation,
pubmed-meshheading:1482379-Serotonin,
pubmed-meshheading:1482379-Tetradecanoylphorbol Acetate,
pubmed-meshheading:1482379-Thrombin
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pubmed:year |
1992
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pubmed:articleTitle |
Evidence for the presence and location of annexins in human platelets.
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pubmed:affiliation |
Department of Pharmacology, University of Bath, Avon, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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