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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1993-2-11
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pubmed:abstractText |
A double blind randomized trial was performed on 58 healthy Polynesian Wuchereria bancrofti carriers, they were randomly allocated to treatments with repeated annual or semi-annual doses of ivermectin 100 mcg/kg or diethylcarbamazine (DEC) 3 mg/kg, or with repeated annual doses of DEC 6 mg/kg. After the 12-month treatment, the clearance of microfilaremia was complete in 7 of the 23 carriers treated with ivermectin and in 3 of the 35 treated with DEC. Nine months after that treatment, the lowest mean microfilaremia was observed in the carriers treated with 3 successive semi-annual doses of DEC 3 mg/kg. Adverse reactions were comparable in carriers treated with ivermectin and in those treated with DEC, and did not interfere with daily activities of treated subjects.
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pubmed:language |
fre
|
pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0398-7620
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
307-12
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1480807-Adolescent,
pubmed-meshheading:1480807-Adult,
pubmed-meshheading:1480807-Animals,
pubmed-meshheading:1480807-Diethylcarbamazine,
pubmed-meshheading:1480807-Dose-Response Relationship, Drug,
pubmed-meshheading:1480807-Double-Blind Method,
pubmed-meshheading:1480807-Elephantiasis,
pubmed-meshheading:1480807-Humans,
pubmed-meshheading:1480807-Ivermectin,
pubmed-meshheading:1480807-Male,
pubmed-meshheading:1480807-Middle Aged,
pubmed-meshheading:1480807-Wuchereria bancrofti
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pubmed:year |
1992
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pubmed:articleTitle |
[Comparative efficacy of annual and semi-annual doses of ivermectin or diethylcarbamazine for the prevention of lymphatic filariasis].
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pubmed:affiliation |
Institut Territorial de Recherches Médicales Louis Malardé, Tahiti, Polynésie Française.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
English Abstract,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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