Linked Life Data

147867

Source:http://linkedlifedata.com/resource/pubmed/id/147867

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1978-6-28
pubmed:abstractText
Sulphatides (ceramide galactose-3-sulphate) were isolated from human erythrocyte membranes. The amount obtained was 3.3 mg from 6.7 kg of wet cells, or 1.5 X 10(-9) mol per g dry cells. The polar part was shown to be galactose-3-sulphate by chromatographic analysis, infrared spectrometry, and mass spectrometry after solvolytic desulphation. The ceramide part consisted of three major molecular species, sphingosine-palmitic acid, sphingosine-2-hydroxypalmitic acid, and phytosphingosine-2-hydroxypalmitic acid, as shown by thin-layer chromatography, mass spectrometry of galactosylceramides after desulphation, and gas chromatography of components after hydrolysis. The composition differed from other human erythrocyte sphingolipids. Although the amount of sulphatides is very low for erythrocyte, the ratio of sulphatide concentration and Na+-K+-ATPase activity [EC 3.6.1.3] is similar to the situation found for several animal tissues with an increased level of Na+ transport. This finding is discussed in relation to a recent model of sulphatide function in a transport unit for Na+ and K+ (cofactor site model).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0021-924X
pubmed:author
pubmed:issnType
Print
pubmed:volume
83
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
813-9
pubmed:dateRevised
2007-12-19
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
The identification of sulphatides in human erythrocyte membrane and their relation to sodium-potassium dependent adenosine triphosphatase.
pubmed:publicationType
Journal Article