|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0008633,
umls-concept:C0017337,
umls-concept:C0024779,
umls-concept:C0086418,
umls-concept:C0114838,
umls-concept:C0242827,
umls-concept:C0870432,
umls-concept:C1416882,
umls-concept:C1420213,
umls-concept:C1555465,
umls-concept:C1705417
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|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1993-2-10
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|
pubmed:abstractText |
The human dopamine transporter (DAT1) gene is localized to chromosome 5p15.3 by in situ hybridization and PCR amplification of rodent somatic cell hybrid DNA. Analysis of a 40-bp repeat in the 3' untranslated region of the message revealed variable numbers of the repeat ranging from 3 to 11 copies. These results will aid in the investigation of a role for this gene in genetic disorders of the dopaminergic system in humans.
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pubmed:grant |
|
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0888-7543
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1104-6
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|
pubmed:dateRevised |
2007-11-14
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|
pubmed:meshHeading |
pubmed-meshheading:1478653-Animals,
pubmed-meshheading:1478653-Autoradiography,
pubmed-meshheading:1478653-Base Sequence,
pubmed-meshheading:1478653-Carrier Proteins,
pubmed-meshheading:1478653-Chromosome Mapping,
pubmed-meshheading:1478653-Chromosomes, Human, Pair 15,
pubmed-meshheading:1478653-DNA,
pubmed-meshheading:1478653-Dopamine Plasma Membrane Transport Proteins,
pubmed-meshheading:1478653-Humans,
pubmed-meshheading:1478653-Hybrid Cells,
pubmed-meshheading:1478653-In Situ Hybridization,
pubmed-meshheading:1478653-Membrane Glycoproteins,
pubmed-meshheading:1478653-Membrane Transport Proteins,
pubmed-meshheading:1478653-Molecular Sequence Data,
pubmed-meshheading:1478653-Nerve Tissue Proteins,
pubmed-meshheading:1478653-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:1478653-Rodentia
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|
pubmed:year |
1992
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|
pubmed:articleTitle |
Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR.
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|
pubmed:affiliation |
Laboratory of Molecular Neurobiology, National Institute on Drug Abuse, Baltimore, MD 21224.
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|
