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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
1993-2-8
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pubmed:abstractText |
On pregnancy day 12 101/H and CBA mice were injected intraperitoneally 2.5 mg/kg bw thiophosphamide. 3.5-month-old male offspring were sacrificed. The drug effect on the testes was evaluated by karyologic analysis of the germ cell generations on stage 7 of the seminiferous epithelium cycle. A reliable reduction in the number of spermatogonia A, preleptotene and pachytene spermatocytes and spermatids at development stage 7 was found in 101/H mice. There were interspecific differences in spermatogenesis intensity in intact animals and recovery of germ cell pool after thiophosphamide action inducing toxicity.
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pubmed:language |
rus
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0365-9615
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
114
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
307-8
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pubmed:dateRevised |
2008-10-8
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pubmed:meshHeading |
pubmed-meshheading:1477370-Age Factors,
pubmed-meshheading:1477370-Animals,
pubmed-meshheading:1477370-Female,
pubmed-meshheading:1477370-Fetus,
pubmed-meshheading:1477370-Male,
pubmed-meshheading:1477370-Mice,
pubmed-meshheading:1477370-Mice, Inbred CBA,
pubmed-meshheading:1477370-Mice, Inbred Strains,
pubmed-meshheading:1477370-Pregnancy,
pubmed-meshheading:1477370-Spermatids,
pubmed-meshheading:1477370-Spermatogenesis,
pubmed-meshheading:1477370-Spermatozoa,
pubmed-meshheading:1477370-Thiotepa
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pubmed:year |
1992
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pubmed:articleTitle |
[Effect of antenatal action of Thio-Tepa on spermatogenesis of mature 101/N and CBA mice].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|