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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1993-2-5
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pubmed:abstractText |
Mycobacterium kansasii is a photochromogenic nontuberculous mycobacterium that usually causes infections of the respiratory tract in humans. Although spontaneous resolution of infection has been reported, most patients require antimycobacterial therapy. A three- or four-drug combination--isoniazid, rifampin, and ethambutol and/or streptomycin--usually is prescribed. For evaluation of a new drug, a randomized, double-blind or evaluator-blinded, active-control comparative study design is recommended. Treatment should continue for 18-24 months, and follow-up evaluations should be conducted every 6 months for 3 years. Microbiological outcome is paramount.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1058-4838
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S307-12
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:1477246-Anti-Infective Agents,
pubmed-meshheading:1477246-Clinical Protocols,
pubmed-meshheading:1477246-Clinical Trials, Phase I as Topic,
pubmed-meshheading:1477246-Clinical Trials, Phase II as Topic,
pubmed-meshheading:1477246-Clinical Trials, Phase III as Topic,
pubmed-meshheading:1477246-Clinical Trials as Topic,
pubmed-meshheading:1477246-Humans,
pubmed-meshheading:1477246-Mycobacterium Infections, Nontuberculous,
pubmed-meshheading:1477246-Research Design
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pubmed:year |
1992
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pubmed:articleTitle |
Evaluation of new anti-infective drugs for the treatment of disease caused by Mycobacterium kansasii and other mycobacteria. Infectious Diseases Society of America and the Food and Drug Administration.
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pubmed:affiliation |
Chest Service, San Francisco General Hospital, California 94110.
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pubmed:publicationType |
Journal Article,
Guideline,
Research Support, U.S. Gov't, P.H.S.,
Practice Guideline
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