Source:http://linkedlifedata.com/resource/pubmed/id/14764942
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-4-30
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pubmed:abstractText |
Spontaneously hypercholesterolemic (SHC) rats develop hypercholesterolemia and focal glomerular sclerosis, and have been thought to be a model of lipid-induced glomerular injury. However, recent studies suggest that the hypercholesterolemia might be due to secondary mechanisms by massive proteinuria. The purpose of the present study was to determine in SHC rats the effects of a high cholesterol diet on serum lipid profiles and renal function/histology, and to examine whether or not the model of lipid-induced renal injury could be developed in a short period of the time. The effects of probucol were also studied.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1420-4096
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2004 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
96-104
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pubmed:meshHeading |
pubmed-meshheading:14764942-Animals,
pubmed-meshheading:14764942-Anticholesteremic Agents,
pubmed-meshheading:14764942-Blood Pressure,
pubmed-meshheading:14764942-Cholesterol, Dietary,
pubmed-meshheading:14764942-Dose-Response Relationship, Drug,
pubmed-meshheading:14764942-Hypercholesterolemia,
pubmed-meshheading:14764942-Immunohistochemistry,
pubmed-meshheading:14764942-Kidney,
pubmed-meshheading:14764942-Male,
pubmed-meshheading:14764942-Microscopy, Electron,
pubmed-meshheading:14764942-Probucol,
pubmed-meshheading:14764942-Proteinuria,
pubmed-meshheading:14764942-Rats,
pubmed-meshheading:14764942-Rats, Inbred Strains,
pubmed-meshheading:14764942-Severity of Illness Index
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pubmed:year |
2004
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pubmed:articleTitle |
Effects of probucol on renal function and urinary protein excretion in spontaneously hypercholesterolemic rats fed a normal or high cholesterol diet.
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pubmed:affiliation |
Department of Nephrology and Endocrinology, School of Medicine, University of Tokyo, Tokyo, Japan. akihide-tky@umin.ac.jp
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pubmed:publicationType |
Journal Article
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