Source:http://linkedlifedata.com/resource/pubmed/id/14764054
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-2-6
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pubmed:abstractText |
It has been suggested that WT-1 is helpful in distinguishing a primary ovarian serous carcinoma (OSC) from a primary uterine serous carcinoma (USC). Since both neoplasms are often disseminated at diagnosis and since USC often spreads to the ovary and vice versa, it may be difficult to ascertain the primary site. This is important, since adjuvant therapies for OSC and USC may differ. WT-1 staining patterns also differ between OSC and ovarian endometrioid carcinoma and so it is possible that WT-1 may assist in the distinction of these two neoplasms, which is sometimes problematic, especially with poorly differentiated tumours. This study aims to document the value of WT-1 in these settings. Cases of ovarian borderline serous tumour, primary peritoneal serous carcinoma (PPSC) and uterine endometrioid carcinoma were also studied.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0309-0167
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
109-15
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14764054-Carcinoma, Endometrioid,
pubmed-meshheading:14764054-Cystadenocarcinoma, Serous,
pubmed-meshheading:14764054-Female,
pubmed-meshheading:14764054-Humans,
pubmed-meshheading:14764054-Immunohistochemistry,
pubmed-meshheading:14764054-Ovarian Neoplasms,
pubmed-meshheading:14764054-Tumor Markers, Biological,
pubmed-meshheading:14764054-Uterine Neoplasms,
pubmed-meshheading:14764054-WT1 Proteins
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pubmed:year |
2004
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pubmed:articleTitle |
WT-1 assists in distinguishing ovarian from uterine serous carcinoma and in distinguishing between serous and endometrioid ovarian carcinoma.
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pubmed:affiliation |
Department of Pathology, Royal Group of Hospitals Trust, Belfast, UK.
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pubmed:publicationType |
Journal Article,
Comparative Study
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