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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1993-2-3
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pubmed:abstractText |
The clinical usefulness of a hypoallergenic rice (HRS-1) which was produced by enzymatic decomposition of the constituent proteins of original rice was evaluated in a multicentre study in 44 subjects with recalcitrant atopic dermatitis (AD), who were suspected of having rice allergy. The subjects were fed for at least 4 weeks with HRS-1 instead of eliminating both regular rice and wheat from their daily diet. The extent of overall skin lesions was expressed by using the AD affected area and severity index (ADASI). A statistically significant decrease in ADASI was observed at the 2nd and the 4th week readings and at the end of the study. A provocation test with regular rice was carried out in 5 of 44 subjects following the HRS-1 therapy. An obvious increase in ADASI was found in all of these 5 cases just after this procedure. On final evaluation, 77% of the patients tested showed 'moderate' to 'remarkable' improvement, and 59% of the patients a 'moderate' to 'remarkable' reduction in use of the steroid ointment concomitantly used for the treatment. Finally, HRS-1 was evaluated as 'useful' or 'very useful' in 69% of the subjects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0365-8341
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
176
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
108-12
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1476020-Adolescent,
pubmed-meshheading:1476020-Adult,
pubmed-meshheading:1476020-Child,
pubmed-meshheading:1476020-Child, Preschool,
pubmed-meshheading:1476020-Clinical Trials as Topic,
pubmed-meshheading:1476020-Dermatitis, Atopic,
pubmed-meshheading:1476020-Female,
pubmed-meshheading:1476020-Food Hypersensitivity,
pubmed-meshheading:1476020-Humans,
pubmed-meshheading:1476020-Infant,
pubmed-meshheading:1476020-Male,
pubmed-meshheading:1476020-Oryza sativa
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pubmed:year |
1992
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pubmed:articleTitle |
Mass trial of hypoallergenic rice (HRS-1) produced by enzymatic digestion in atopic dermatitis with suspected rice allergy. HRS-1 Research Group.
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pubmed:affiliation |
Dept. Dermatol., Yokohama City Univ. School of Med., Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
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