Linked Life Data

14759351

Source:http://linkedlifedata.com/resource/pubmed/id/14759351

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2004-2-4
pubmed:abstractText
The presence, implications, and approach to mitral valvular disease in the setting of a cardiomyopathy has recently become a focal issue for discussion. Although recent evidence suggests that mitral regurgitation confers a poor prognosis in heart failure, the true prevalence of mitral regurgitation as well as its pathogenic contribution to prognosis in heart failure remains uncertain. Whereas angiotensin-converting enzyme inhibitors have not been demonstrated to favorably alter mitral regurgitation, treatment with b-blockers or cardiac resynchronization therapy has been shown to induce regression of ventricular dilation, with consequent decrease in mitral regurgitation. Surgical valve reconstruction by undersized ring annuloplasty appears promising, but optimal results require skilled surgical expertise. Even in highly experienced hands, intermediate outcomes appear to be inferior to those of cardiac transplantation. Percutaneous mitral valve repair remains an investigational procedure that warrants further clinical research.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1523-3782
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
96-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Mitral regurgitation in chronic heart failure: more questions than answers?
pubmed:affiliation
Department of Cardiovascular Medicine, Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USA. mmehra@Ochsner.org
pubmed:publicationType
Journal Article, Review