Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2 Suppl Pediatrics
pubmed:dateCreated
2004-2-4
pubmed:abstractText
Few studies have been conducted to investigate the genomic survey of oncogene amplification in medulloblastoma. Low frequency of N-myc, C-myc, and epidermal grow factor receptor (EGFR) gene amplification (< 10%) has been reported in medulloblastoma. Previous comparative genomic hybridization (CGH) study of primary medulloblastomas has revealed chromosomal amplification on 2p21, 3p, 5p15.3, 7q, 8q24, 11q22.3, and 17q. The aim of this study was to detect common oncogenes involved in medulloblastoma tumorigenesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-3085
pubmed:author
pubmed:issnType
Print
pubmed:volume
100
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
187-93
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:14758948-Adolescent, pubmed-meshheading:14758948-Adult, pubmed-meshheading:14758948-Blotting, Western, pubmed-meshheading:14758948-Cerebellar Neoplasms, pubmed-meshheading:14758948-Child, pubmed-meshheading:14758948-Child, Preschool, pubmed-meshheading:14758948-DNA, Neoplasm, pubmed-meshheading:14758948-Female, pubmed-meshheading:14758948-Gene Amplification, pubmed-meshheading:14758948-Gene Expression Profiling, pubmed-meshheading:14758948-Gene Expression Regulation, Neoplastic, pubmed-meshheading:14758948-Gene Frequency, pubmed-meshheading:14758948-Genetic Markers, pubmed-meshheading:14758948-Humans, pubmed-meshheading:14758948-In Situ Hybridization, Fluorescence, pubmed-meshheading:14758948-In Situ Nick-End Labeling, pubmed-meshheading:14758948-Male, pubmed-meshheading:14758948-Medulloblastoma, pubmed-meshheading:14758948-Nucleic Acid Hybridization, pubmed-meshheading:14758948-Oligonucleotide Array Sequence Analysis, pubmed-meshheading:14758948-Oncogenes
pubmed:year
2004
pubmed:articleTitle
Detection of oncogene amplifications in medulloblastomas by comparative genomic hybridization and array-based comparative genomic hybridization.
pubmed:affiliation
Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, China.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't