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rdf:type |
|
|
lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-2-3
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pubmed:abstractText |
The role of glucocorticoids (GCs) in the pathogenesis of laminitis is incompletely understood. Local tissue activity of GC is regulated by the steroid converting enzyme, 11beta-hydroxysteroid dehydrogenase-1 (11beta-HSD-1). Changes in integumentary (skin and hoof lamellar) 11beta-HSD activity occurring during laminitis could affect the extent to which GCs are involved in its development.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0425-1644
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
36
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|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
41-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14756370-11-beta-Hydroxysteroid Dehydrogenase Type 1,
pubmed-meshheading:14756370-Acute Disease,
pubmed-meshheading:14756370-Animals,
pubmed-meshheading:14756370-Chronic Disease,
pubmed-meshheading:14756370-Female,
pubmed-meshheading:14756370-Foot Diseases,
pubmed-meshheading:14756370-Glucocorticoids,
pubmed-meshheading:14756370-Hoof and Claw,
pubmed-meshheading:14756370-Horse Diseases,
pubmed-meshheading:14756370-Horses,
pubmed-meshheading:14756370-Hydrocortisone,
pubmed-meshheading:14756370-Inflammation,
pubmed-meshheading:14756370-Lameness, Animal,
pubmed-meshheading:14756370-Male,
pubmed-meshheading:14756370-Skin
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pubmed:year |
2004
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|
pubmed:articleTitle |
Tissue-specific dysregulation of cortisol metabolism in equine laminitis.
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pubmed:affiliation |
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri at Columbia, Missouri 65211, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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