Source:http://linkedlifedata.com/resource/pubmed/id/14754980
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
2004-2-2
|
pubmed:abstractText |
Allergic rhinitis is common and on the rise. Antihistamines are the mainstay of treatment and are the most commonly prescribed drugs in Singapore. Treatment-related sedation and its effect on cognition are a major concern. First- and second-generation antihistamines show varying degrees of sedation, but to date, objective studies in children are lacking. The objective of this study was to assess the sedating effect of cetirizine (second-generation antihistamine) and chlorpheniramine (first-generation antihistamine) compared with placebo using an objective neurophysiological test.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
1098-4275
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:volume |
113
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
e116-21
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:14754980-Adolescent,
pubmed-meshheading:14754980-Central Nervous System,
pubmed-meshheading:14754980-Cetirizine,
pubmed-meshheading:14754980-Child,
pubmed-meshheading:14754980-Chlorpheniramine,
pubmed-meshheading:14754980-Cross-Over Studies,
pubmed-meshheading:14754980-Double-Blind Method,
pubmed-meshheading:14754980-Event-Related Potentials, P300,
pubmed-meshheading:14754980-Female,
pubmed-meshheading:14754980-Histamine H1 Antagonists,
pubmed-meshheading:14754980-Histamine H1 Antagonists, Non-Sedating,
pubmed-meshheading:14754980-Humans,
pubmed-meshheading:14754980-Male,
pubmed-meshheading:14754980-Prospective Studies,
pubmed-meshheading:14754980-Rhinitis, Allergic, Perennial,
pubmed-meshheading:14754980-Sleep
|
pubmed:year |
2004
|
pubmed:articleTitle |
Central nervous system side effects of first- and second-generation antihistamines in school children with perennial allergic rhinitis: a randomized, double-blind, placebo-controlled comparative study.
|
pubmed:affiliation |
Department of Paediatrics, National University of Singapore, Singapore.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|