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rdf:type |
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lifeskim:mentions |
umls-concept:C0018787,
umls-concept:C0021079,
umls-concept:C0021080,
umls-concept:C0031327,
umls-concept:C0040808,
umls-concept:C0085542,
umls-concept:C0205174,
umls-concept:C0205653,
umls-concept:C0376387,
umls-concept:C0851347,
umls-concept:C1521725
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pubmed:issue |
1
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pubmed:dateCreated |
2004-1-29
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pubmed:abstractText |
In adults, pravastatin reduces the development and progression of transplant vasculopathy, the main long-term risk after cardiac transplantation. The pharmacokinetics of pravastatin is not known in children taking calcineurin inhibitors. Our aim was to determine the single-dose pharmacokinetics and short-term safety of pravastatin in children undergoing regular triple-drug immunosuppressive therapy after cardiac transplantation.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anticholesteremic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Azathioprine,
http://linkedlifedata.com/resource/pubmed/chemical/Calcineurin,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclosporine,
http://linkedlifedata.com/resource/pubmed/chemical/Immunosuppressive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Methylprednisolone,
http://linkedlifedata.com/resource/pubmed/chemical/Mycophenolic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Pravastatin,
http://linkedlifedata.com/resource/pubmed/chemical/Tacrolimus,
http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides,
http://linkedlifedata.com/resource/pubmed/chemical/mycophenolate mofetil
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0009-9236
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
101-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:14749696-Administration, Oral,
pubmed-meshheading:14749696-Adolescent,
pubmed-meshheading:14749696-Anticholesteremic Agents,
pubmed-meshheading:14749696-Area Under Curve,
pubmed-meshheading:14749696-Azathioprine,
pubmed-meshheading:14749696-Calcineurin,
pubmed-meshheading:14749696-Child,
pubmed-meshheading:14749696-Child, Preschool,
pubmed-meshheading:14749696-Cholesterol,
pubmed-meshheading:14749696-Cholesterol, HDL,
pubmed-meshheading:14749696-Cholesterol, LDL,
pubmed-meshheading:14749696-Cyclosporine,
pubmed-meshheading:14749696-Drug Interactions,
pubmed-meshheading:14749696-Female,
pubmed-meshheading:14749696-Heart Transplantation,
pubmed-meshheading:14749696-Humans,
pubmed-meshheading:14749696-Immunosuppressive Agents,
pubmed-meshheading:14749696-Male,
pubmed-meshheading:14749696-Methylprednisolone,
pubmed-meshheading:14749696-Mycophenolic Acid,
pubmed-meshheading:14749696-Pravastatin,
pubmed-meshheading:14749696-Tacrolimus,
pubmed-meshheading:14749696-Triglycerides
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pubmed:year |
2004
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pubmed:articleTitle |
Pharmacokinetics and pharmacodynamics of pravastatin in pediatric and adolescent cardiac transplant recipients on a regimen of triple immunosuppression.
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pubmed:affiliation |
Hospital for Children and Adolescents and Department of Clinical Pharacology, University of Helsinki, Finland.
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pubmed:publicationType |
Journal Article
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