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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1993-2-4
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pubmed:databankReference | |
pubmed:abstractText |
Evidence is provided for the presence of retrosequences (also named retroposons) arising from Adh in the Drosophila subobscura genome. Restriction analysis and primary structure of two different retrosequence-containing clones, S812 and S135, are reported. The fact that these retrosequences lack introns and a recognizable promoter strongly supports their retrotranscriptional origin. Adjacent to the two retrosequences analyzed, a middle repetitive DNA element has been found which bears no clear similarity to any sequence reported to date in the GenBank/EMBL Data Library. A comparative analysis of these retrosequences with the functional Adh gene of D. subobscura is presented. In addition, a model concerning the origin, functionality, and propagation of these genome elements is discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0022-2844
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
35
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pubmed:geneSymbol |
Adh
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
492-501
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:1474603-Alcohol Dehydrogenase,
pubmed-meshheading:1474603-Animals,
pubmed-meshheading:1474603-Base Sequence,
pubmed-meshheading:1474603-Biological Evolution,
pubmed-meshheading:1474603-Blotting, Southern,
pubmed-meshheading:1474603-DNA,
pubmed-meshheading:1474603-Drosophila,
pubmed-meshheading:1474603-Molecular Sequence Data,
pubmed-meshheading:1474603-Polymerase Chain Reaction,
pubmed-meshheading:1474603-Proteins,
pubmed-meshheading:1474603-Pseudogenes,
pubmed-meshheading:1474603-Restriction Mapping,
pubmed-meshheading:1474603-Transcription, Genetic
|
pubmed:year |
1992
|
pubmed:articleTitle |
Evidence for retrotranscription of protein-coding genes in the Drosophila subobscura genome.
|
pubmed:affiliation |
Departament de Genètica, Facultat de Biologia, Universitat de Barcelona, Spain.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|