rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-4
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pubmed:dateCreated |
2004-1-26
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pubmed:abstractText |
Two or three decades ago, cancer pain was treated by surgical/chemical hypophysectomy. In one report, the control of central pain (thalamic pain syndrome) was also approached with chemical hypophysectomy. Although in most of the patients these treatments resulted in a decrease in severe pain, concomitantly severe adverse effects (panhypopituitarism, diabetes insipidus and visual dysfunction) occurred in most patients. This historical evidence prompted us to perform Gamma Knife surgery (GKS) for this kind of intractable severe pain using a high irradiation dose to the pituitary stalk/gland. In the majority of patients, marked pain relief was achieved, surprisingly without any of the complications mentioned above.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:issn |
1011-6125
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pubmed:author |
pubmed-author:ChernovMikhailM,
pubmed-author:HayashiMotohiroM,
pubmed-author:HoRobert T KRT,
pubmed-author:HoriTomokatsuT,
pubmed-author:IzawaMasahiroM,
pubmed-author:KatayamaYokoY,
pubmed-author:KawakamiYorikoY,
pubmed-author:KouyamaNobuoN,
pubmed-author:LiscakRomanR,
pubmed-author:TairaTakaomiT,
pubmed-author:TakakuraKintomoK,
pubmed-author:YuChung PingCP
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pubmed:copyrightInfo |
Copyright 2003 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
81
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
75-83
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:14742968-Bone Neoplasms,
pubmed-meshheading:14742968-Breast Neoplasms,
pubmed-meshheading:14742968-Female,
pubmed-meshheading:14742968-Humans,
pubmed-meshheading:14742968-Hypophysectomy,
pubmed-meshheading:14742968-Male,
pubmed-meshheading:14742968-Pain,
pubmed-meshheading:14742968-Pituitary Gland,
pubmed-meshheading:14742968-Prospective Studies,
pubmed-meshheading:14742968-Prostatic Neoplasms,
pubmed-meshheading:14742968-Radiosurgery,
pubmed-meshheading:14742968-Thalamus,
pubmed-meshheading:14742968-Treatment Outcome,
pubmed-meshheading:14742968-beta-Endorphin
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pubmed:year |
2003
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pubmed:articleTitle |
Role of pituitary radiosurgery for the management of intractable pain and potential future applications.
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pubmed:affiliation |
Department of Neurosurgery, Neurological Institute, Tokyo Women's Medical University, Tokyo, Japan. GKRmoto@aol.com
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Multicenter Study
|