Linked Life Data

14741272

Source:http://linkedlifedata.com/resource/pubmed/id/14741272

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2004-1-26
pubmed:abstractText
We have demonstrated that thiol-bearing analogues of alpha-chymotrysin (alpha-CT) substrates such as (S)-(1-benzyl-2-thiolethyl)-carbamic acid, benzyl ester (3) inhibits alpha-CT, a prototypical serine protease, in the presence of Zn(II) ion. They constitute a novel class of small molecule inhibitors for alpha-CT believed to inhibit the enzyme by forming a ternary complex consisting of alpha-CT, Zn(II) ion, and the inhibitor.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0960-894X
pubmed:author
pubmed:issnType
Print
pubmed:day
9
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
701-5
pubmed:dateRevised
2009-1-8
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Inhibition of alpha-chymotrypsin with thiol-bearing substrate analogues in the presence of zinc ion.
pubmed:affiliation
Department of Chemistry, Pohang University of Science and Technology, San 31Hyojadong, Pohang 790-784, South Korea.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't