rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2004-1-26
|
pubmed:abstractText |
The synthesis of several novel coumarin derivatives with a 7-azomethine linkage was carried out starting from 7-formyl-coumarin. The compounds were tested in vivo for their anti-inflammatory activity and in vitro for their antioxidant ability. Compounds 3a and 3e possess significant protection against carrageenin induced rat paw edema.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0960-894X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
9
|
pubmed:volume |
14
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
611-4
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:14741253-Animals,
pubmed-meshheading:14741253-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:14741253-Antioxidants,
pubmed-meshheading:14741253-Azo Compounds,
pubmed-meshheading:14741253-Carrageenan,
pubmed-meshheading:14741253-Coumarins,
pubmed-meshheading:14741253-Edema,
pubmed-meshheading:14741253-Hindlimb,
pubmed-meshheading:14741253-Inflammation,
pubmed-meshheading:14741253-Molecular Structure,
pubmed-meshheading:14741253-Rats,
pubmed-meshheading:14741253-Structure-Activity Relationship
|
pubmed:year |
2004
|
pubmed:articleTitle |
Synthesis and biological evaluation of novel coumarin derivatives with a 7-azomethine linkage.
|
pubmed:affiliation |
Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|