|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2004-1-23
|
|
pubmed:abstractText |
The Metoprolol CR/XL Randomized Intervention Trial in Chronic Heart Failure (MERIT-HF), the Cardiac Insufficiency Bisoprolol Study II (CIBIS-II), and the Carvedilol Prospective Randomized Cumulative Survival Study (COPERNICUS) have all demonstrated highly significant positive effects on total mortality as well as total mortality plus all-cause hospitalization in patients with heart failure. While none of these trials are large enough to provide definitive results in any particular subgroup, it is of interest for physicians to examine the consistency of results as regards efficacy and safety for various subgroups or risk groups.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
1385-2264
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
7
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
264-75
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:14739726-Adrenergic beta-Antagonists,
pubmed-meshheading:14739726-African Continental Ancestry Group,
pubmed-meshheading:14739726-Diabetic Angiopathies,
pubmed-meshheading:14739726-Heart Failure,
pubmed-meshheading:14739726-Humans,
pubmed-meshheading:14739726-Hypertension,
pubmed-meshheading:14739726-Meta-Analysis as Topic,
pubmed-meshheading:14739726-Metoprolol,
pubmed-meshheading:14739726-Multicenter Studies as Topic,
pubmed-meshheading:14739726-Myocardial Infarction,
pubmed-meshheading:14739726-Physician's Practice Patterns,
pubmed-meshheading:14739726-Propanolamines,
pubmed-meshheading:14739726-Randomized Controlled Trials as Topic
|
|
pubmed:year |
2003
|
|
pubmed:articleTitle |
How should subgroup analyses affect clinical practice? Insights from the Metoprolol Succinate Controlled-Release/Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF).
|
|
pubmed:affiliation |
Wallenberg Laboratory for Cardiovascular Research, Sahlgrenska University Hospital, Göteborg, Sweden. john.wikstrand@wlab.gu.se
|
|
pubmed:publicationType |
Journal Article
|
