Linked Life Data

14738520

Source:http://linkedlifedata.com/resource/pubmed/id/14738520

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2004-1-23
pubmed:abstractText
Older adults are slower than young adults to think of an item they just saw, that is, to engage or execute (or both) the simple reflective operation of refreshing just-activated information. In addition, they derive less long-term memory benefit from refreshing information. Using functional magnetic resonance imaging (fMRI), we found that relative to young adults, older adults showed reduced refresh-related activity in an area of dorsolateral prefrontal cortex (left middle frontal gyrus, Brodmann's Area 9), but not in other refresh-related areas. This provides strong evidence that a frontal component of the circuit that subserves this basic cognitive process is especially vulnerable to aging. Such a refresh deficit could contribute to poorer performance of older than young adults on a wide range of cognitive tasks.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0956-7976
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
127-32
pubmed:dateRevised
2011-5-20
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
An age-related deficit in prefrontal cortical function associated with refreshing information.
pubmed:affiliation
Yale University, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.