Linked Life Data

1473559

Source:http://linkedlifedata.com/resource/pubmed/id/1473559

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-2-1
pubmed:abstractText
Putative 5-HT4 receptors were investigated in isolated piglet left atria and papillary muscles. In atrial tissues, 5-hydroxytryptamine (5-HT) was a potent positive inotropic agent with a pD2 of 6.7. Its effects were antagonised in a selective and competitive manner by the 5-HT4 receptor antagonist, SDZ 205-557, with a pA2 of 7.3. In contrast to atrial tissues, piglet papillary muscles were virtually unresponsive to 5-HT 10(-8)-10(-3) M, suggesting that functional cardiac 5-HT4 receptors are not present in ventricular tissue.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0014-2999
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
229
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
105-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
5-HT4 receptors, present in piglet atria and sensitive to SDZ 205-557, are absent in papillary muscle.
pubmed:affiliation
Synthélabo Recherche (L.E.R.S.), Department of Biology, Bagneux, France.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro