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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-1-21
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pubmed:abstractText |
The MHC class II molecules have been recognized as signaling receptors for more than a decade, and recent work has revealed the importance of their signaling for the immune response. Today, we know that the function of MHC class II molecules on antigen-presenting cells (APCs) is not limited to their role as antigen-presenting structures; they are flexible receptors that, by triggering a variety of signaling pathways, can regulate APC activities from proliferation and maturation to apoptosis. Recent advances have provided insights into how these molecules might accommodate such regulation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0952-7915
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
108-13
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:14734118-Animals,
pubmed-meshheading:14734118-Antigen Presentation,
pubmed-meshheading:14734118-Antigen-Presenting Cells,
pubmed-meshheading:14734118-B-Lymphocytes,
pubmed-meshheading:14734118-Histocompatibility Antigens Class II,
pubmed-meshheading:14734118-Membrane Microdomains,
pubmed-meshheading:14734118-Protein Kinase C,
pubmed-meshheading:14734118-Protein-Tyrosine Kinases,
pubmed-meshheading:14734118-Receptors, Antigen,
pubmed-meshheading:14734118-Signal Transduction,
pubmed-meshheading:14734118-T-Lymphocytes
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pubmed:year |
2004
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pubmed:articleTitle |
MHC class II signaling in antigen-presenting cells.
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pubmed:affiliation |
Institut Universitaire d'Hématologie, IFR105, Hôpital Saint Louis AP-HP, 10 rue Claude Vellefaux, 75475 Paris, France. Reem.Al-Daccak@bhdc.jussieu.fr
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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