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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-1-21
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pubmed:abstractText |
The role of the G alpha q/11-mediated signal transduction pathway in angiotensin II (AngII) induced cardiac hypertrophy remains unclear. This study was to investigate the role of the G alpha q/11 signal transduction pathway in the development of cardiac hypertrophy in 2K1C hypertensive rats and in cultured neonatal rat ventricular myocytes (NRVMs) and to elucidate the effects of the pathway on AngII induced cardiac hypertrophy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II,
http://linkedlifedata.com/resource/pubmed/chemical/GTP-Binding Protein alpha...,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipase C beta,
http://linkedlifedata.com/resource/pubmed/chemical/Plcb3 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Angiotensin, Type 1,
http://linkedlifedata.com/resource/pubmed/chemical/Type C Phospholipases
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0366-6999
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
117
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
88-93
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:14733781-Angiotensin II,
pubmed-meshheading:14733781-Animals,
pubmed-meshheading:14733781-Cardiomegaly,
pubmed-meshheading:14733781-Cells, Cultured,
pubmed-meshheading:14733781-GTP-Binding Protein alpha Subunits, Gq-G11,
pubmed-meshheading:14733781-Hypertension,
pubmed-meshheading:14733781-Isoenzymes,
pubmed-meshheading:14733781-Male,
pubmed-meshheading:14733781-Mitogen-Activated Protein Kinase 3,
pubmed-meshheading:14733781-Mitogen-Activated Protein Kinases,
pubmed-meshheading:14733781-Myocytes, Cardiac,
pubmed-meshheading:14733781-Phospholipase C beta,
pubmed-meshheading:14733781-Rats,
pubmed-meshheading:14733781-Rats, Wistar,
pubmed-meshheading:14733781-Receptor, Angiotensin, Type 1,
pubmed-meshheading:14733781-Signal Transduction,
pubmed-meshheading:14733781-Type C Phospholipases,
pubmed-meshheading:14733781-Up-Regulation
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pubmed:year |
2004
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pubmed:articleTitle |
Angiotensin II induced upregulation of G alpha q/11, phospholipase C beta 3 and extracellular signal-regulated kinase 1/2 via angiotensin II type 1 receptor.
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pubmed:affiliation |
Department of Cardiology, Peking Union Medical College Hospital, Beijing 100730, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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