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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1993-2-1
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pubmed:abstractText |
Molt induced by infusion of a gonadotropin-releasing hormone agonist (GnRH-A, ([D-leu6,Pro9]-GnRH N-ethylamide]) or feed withdrawal (FW) has been used as a model to study interactions between ovarian activity and thymosin beta 4 during molting in domestic hens. Thirty-three laying hens were divided into three groups: 1, controls, 2, GnRH-A infusion induced molt (GnRH-A), or 3, FW induced molt. All groups had reduced daylength. Blood was sampled weekly and assayed for concentrations of thymosin beta 4 and progesterone (P4). Plasma P4 concentrations were significantly depressed in both treatment groups compared to controls, indicating ovarian regression. Plasma P4 concentrations had returned to control values in the GnRH-A group by 28 d after the start of treatment, while P4 was still depressed in the FW group at day 42 when the experiment ended. Plasma concentrations of thymosin beta 4 were elevated relative to controls from day 7 through day 14 in the GnRH-A group and from day 7 until day 28 in the FW group. It is concluded that plasma concentrations of thymosin beta 4 are elevated during molting in domestic hens, but the elevation is not attributable to depressed P4 concentrations.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0739-7240
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
297-304
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:1473348-Animals,
pubmed-meshheading:1473348-Chickens,
pubmed-meshheading:1473348-Feathers,
pubmed-meshheading:1473348-Female,
pubmed-meshheading:1473348-Food Deprivation,
pubmed-meshheading:1473348-Leuprolide,
pubmed-meshheading:1473348-Ovary,
pubmed-meshheading:1473348-Ovulation,
pubmed-meshheading:1473348-Progesterone,
pubmed-meshheading:1473348-Thymosin
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pubmed:year |
1992
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pubmed:articleTitle |
Effect of ovarian regression and molt on plasma concentrations of thymosin beta 4 in domestic hens (Gallus domesticus).
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pubmed:affiliation |
Department of Physiology and Biophysics, University of Illinois, Urbana 61801.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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