Source:http://linkedlifedata.com/resource/pubmed/id/14731544
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
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| pubmed:dateCreated |
2004-1-20
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| pubmed:abstractText |
The two DNA-binding subunits of the transcription factor NF-kappa B, the products of the rel oncogene family and the product of the developmental control gene dorsal of Drosophila are homologous within a 300 amino acid region. This sequence represents a novel DNA-binding and dimerization domain. The access of the NF-kappa B/Rel/dorsal (NRD) transcription factor family to the cell nucleus is regulated. There is now evidence that functionally and structurally related accessory proteins of NF-kappa B, Rel and dorsal control the nuclear entry as well as DNA-binding activity of the transcription factors. This review summarizes current knowledge about the nuclear-uptake regulatory proteins (NURPs) I kappa B-alpha, I kappa B-beta/pp40 and cactus.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:status |
PubMed-not-MEDLINE
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| pubmed:month |
Nov
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| pubmed:issn |
0962-8924
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
1
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
130-7
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| pubmed:year |
1991
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| pubmed:articleTitle |
Proteins controlling the nuclear uptake of NF-kappa B, Rel and dorsal.
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| pubmed:affiliation |
Laboratorium für Molekulare Biologie der Ludwig-Maximilians-Universität, Genzentrum, Am Klopferspitz, D-8033 Martinsried, FRG.
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| pubmed:publicationType |
Journal Article
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