Linked Life Data

14731542

Source:http://linkedlifedata.com/resource/pubmed/id/14731542

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2004-1-20
pubmed:abstractText
Increasing evidence suggests that the eukaryotic cell cycle is controlled at several checkpoints by different members of a novel class of protein kinase, the cyclin-dependent kinases. To phosphorylate their substrates, these enzymes bind to proteins of the cyclin family--proteins that are synthesized and degraded at specific points in each cell cycle. The most well known of these kinases is the 34 kDa product of the cdc2 gene in fission yeast, p34cdc2; however, several putative cyclin-dependent kinases have now been cloned or identified. Some of these closely resemble p34cdc2. Here we review these new proteins, their potential roles in the cell cycle and the cyclins with which they may interact.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Nov
pubmed:issn
0962-8924
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
117-21
pubmed:year
1991
pubmed:articleTitle
Cyclin-dependent kinases: a new cell cycle motif?
pubmed:affiliation
Molecular Biology and Virology Laboratory, The Salk Institute for Biological Studies, PO Box 85800, San Diego, CA 92186-5800, USA.
pubmed:publicationType
Journal Article