Source:http://linkedlifedata.com/resource/pubmed/id/14730629
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
2004-1-19
|
pubmed:abstractText |
OCH, a synthetic analog of alpha-galactosylceramide with a truncated sphingosine chain, stimulates natural killer T (NKT) cells to produce predominantly Th2 cytokines. Thus, OCH may be a potential agent for the treatment of Th1-mediated autoimmune diseases. This study was designed to evaluate the protective effects of OCH on collagen-induced arthritis (CIA) in mice.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0004-3591
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
50
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
305-13
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:14730629-Animals,
pubmed-meshheading:14730629-Arthritis, Experimental,
pubmed-meshheading:14730629-Galactosylceramides,
pubmed-meshheading:14730629-Interleukin-10,
pubmed-meshheading:14730629-Interleukin-4,
pubmed-meshheading:14730629-Killer Cells, Natural,
pubmed-meshheading:14730629-Mice,
pubmed-meshheading:14730629-Mice, Inbred C57BL,
pubmed-meshheading:14730629-Mice, Knockout,
pubmed-meshheading:14730629-Sphingosine,
pubmed-meshheading:14730629-Th2 Cells
|
pubmed:year |
2004
|
pubmed:articleTitle |
Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of alpha-galactosylceramide.
|
pubmed:affiliation |
National Institute of Neuroscience, NCNP and Juntendo University School of Medicine, Tokyo, Japan. miyake@ncnp.go.jp
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|