Source:http://linkedlifedata.com/resource/pubmed/id/14728102
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
2004-1-19
|
pubmed:abstractText |
Posttraumatic stress disorder (PTSD) is often a chronic disorder, and, though 2 antidepressants are now approved by the U.S. Food and Drug Administration for its treatment, it often remains refractory to pharmacotherapy. The memory of traumatic events, by repeatedly stimulating the hippocampus and amygdala (kindling phenomenon), may alter multiple biological systems, including gamma-aminobutyric acid (GABA) pathways, and eventually lead to the disorder. Tiagabine, a selective GABA reuptake inhibitor, was evaluated as a treatment for PTSD.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0160-6689
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
64
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1421-5
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:14728102-Adult,
pubmed-meshheading:14728102-Antidepressive Agents,
pubmed-meshheading:14728102-Comorbidity,
pubmed-meshheading:14728102-Depressive Disorder, Major,
pubmed-meshheading:14728102-Drug Therapy, Combination,
pubmed-meshheading:14728102-Female,
pubmed-meshheading:14728102-GABA Agonists,
pubmed-meshheading:14728102-Humans,
pubmed-meshheading:14728102-Middle Aged,
pubmed-meshheading:14728102-Nipecotic Acids,
pubmed-meshheading:14728102-Stress Disorders, Post-Traumatic,
pubmed-meshheading:14728102-Treatment Outcome
|
pubmed:year |
2003
|
pubmed:articleTitle |
Tiagabine for posttraumatic stress disorder: a case series of 7 women.
|
pubmed:affiliation |
Rainier Associates, Tacoma, WA 98467, USA. tfletcher2@uswest.net
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|