To evaluate the effects of trazodone on subjective and objective measures of sleep in depressed insomnia patients treated with selective serotonin reuptake inhibitors (SSRIs). SSRIs can exacerbate or cause new insomnia while alleviating other symptoms of depression. Trazodone has been reported to be an effective hypnotic for patients with antidepressant-associated insomnia.
Department of Neurology, Sleep Disorders Unit, Cerrahpasa Medical School, University of Istanbul, Cerrahpasa, 34303 Istanbul, Turkey. kaynak@attglobal.net