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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-1-13
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pubmed:abstractText |
The prothrombin G20210A mutation is associated with increased plasma prothrombin levels and risk of thrombosis. The mechanism by which this mutation leads to increased prothrombin expression is as yet unclear and still the subject of debate.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1538-7933
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
119-27
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:14717975-3' Untranslated Regions,
pubmed-meshheading:14717975-Base Sequence,
pubmed-meshheading:14717975-Binding Sites,
pubmed-meshheading:14717975-Cell Line,
pubmed-meshheading:14717975-Gene Expression,
pubmed-meshheading:14717975-Genes, Regulator,
pubmed-meshheading:14717975-Genes, Reporter,
pubmed-meshheading:14717975-Genetic Variation,
pubmed-meshheading:14717975-Humans,
pubmed-meshheading:14717975-Liver,
pubmed-meshheading:14717975-Luciferases,
pubmed-meshheading:14717975-Molecular Sequence Data,
pubmed-meshheading:14717975-Plasmids,
pubmed-meshheading:14717975-Point Mutation,
pubmed-meshheading:14717975-Poly A,
pubmed-meshheading:14717975-Prothrombin,
pubmed-meshheading:14717975-RNA, Messenger,
pubmed-meshheading:14717975-Transfection,
pubmed-meshheading:14717975-Venous Thrombosis
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pubmed:year |
2004
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pubmed:articleTitle |
G20210A is a functional mutation in the prothrombin gene; effect on protein levels and 3'-end formation.
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pubmed:affiliation |
Hemostasis and Thrombosis Research Center, Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands. hceelie@lumc.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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