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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-1-9
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pubmed:abstractText |
Immunoglobulin G (IgG) antibodies to the steroidogenic enzymes 21-hydroxylase (21OH) and side-chain cleavage enzyme (SCC) are important diagnostic markers for autoimmune Addison's disease and autoimmune polyendocrine syndromes (APS) types I and II. The characterization of autoantibody (IgG) subclasses may reveal information on how tIssue destruction takes place; therefore, IgG subtypes of anti-21OH and anti-SCC antibodies from sera of patients with Addison's disease, APS I and APS II were determined using recombinant 21OH and SCC.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0804-4643
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
150
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
49-56
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14713279-Addison Disease,
pubmed-meshheading:14713279-Antibody Specificity,
pubmed-meshheading:14713279-Autoantibodies,
pubmed-meshheading:14713279-Biological Markers,
pubmed-meshheading:14713279-Cholesterol Side-Chain Cleavage Enzyme,
pubmed-meshheading:14713279-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:14713279-Humans,
pubmed-meshheading:14713279-Immunoglobulin G,
pubmed-meshheading:14713279-Steroid 21-Hydroxylase,
pubmed-meshheading:14713279-T-Lymphocytes
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pubmed:year |
2004
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pubmed:articleTitle |
Autoantibodies against 21-hydroxylase and side-chain cleavage enzyme in autoimmune Addison's disease are mainly immunoglobulin G1.
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pubmed:affiliation |
Division of Endocrinology, Institute of Medicine, Haukeland University Hospital, N-5021, Bergen, Norway. Anette.Boe@med.uib.no
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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