Linked Life Data

14708667

Source:http://linkedlifedata.com/resource/pubmed/id/14708667

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2004-1-7
pubmed:abstractText
Freshly neutralized aluminium (Al) is toxic to a variety of freshwater organisms despite its insolubility at circumneutral pH. Insoluble Al acts exogenously--for example, on the fish gill--thereby impairing respiratory function, and endogenously in grazing and filter-feeding invertebrates following ingestion during drinking and feeding. This paper examines the bioavailability and behavioral toxicity of freshly neutralized Al to the freshwater crayfish Pacifastacus leniusculus exposed to 500 microg L(-1) added Al for 20 days under controlled conditions. We test the hypothesis that aqueous Al is toxic to the crayfish and that this is largely due to the metal's association with the gill rather than following accumulation in the body. Little Al was accumulated in the digestive gland (hepatopancreas) or flexor muscle, but large amounts were associated with the gills, resulting in concentration factors of up to 1 x 10(4). Histochemistry showed that much of this metal was extracellular to the gill epithelium and associated with the mucus layer. Behavioral dysfunction was observed following exposure to Al for five days. Reduction in the amount of Al in the water column, due to binding to snail trail mucus attached to the substrate, reduced the amount of Al associated with the gill and delayed the onset of behavioral dysfunction. We conclude that freshly neutralized Al is toxic to the crayfish and that main site of Al action is the gill.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0090-4341
pubmed:author
pubmed:issnType
Print
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
509-14
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Bioavailability and toxicity of freshly neutralized aluminium to the freshwater crayfish Pacifastacus leniusculus.
pubmed:affiliation
School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, United Kingdom.
pubmed:publicationType
Journal Article