Source:http://linkedlifedata.com/resource/pubmed/id/14707469
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2004-1-6
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pubmed:abstractText |
Clinical history and patch test constitute the two cornerstones in the diagnosis of nickel (Ni) allergy. Due to technical and interpretative limits of the patch test, the in vitro lymphocyte transformation test (LTT) has been developed for confirming contact allergy; however, most studies show an overlap in lymphocyte proliferation between Ni-allergic and nonallergic subjects using the LTT. The aim of this study was to see if the secretion of cytokines, especially interleukin (IL)-10 and IL-17, or the use of T-cell receptor (TCR) Vbeta families in Ni-stimulated primary peripheral blood mononuclear cell (PBMC) cultures might be more useful for discriminating between allergic and nonallergic subjects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1018-2438
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2003 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
132
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
373-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14707469-Adult,
pubmed-meshheading:14707469-CD4-Positive T-Lymphocytes,
pubmed-meshheading:14707469-Dermatitis, Contact,
pubmed-meshheading:14707469-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:14707469-Female,
pubmed-meshheading:14707469-Humans,
pubmed-meshheading:14707469-Immunophenotyping,
pubmed-meshheading:14707469-Interleukin-10,
pubmed-meshheading:14707469-Interleukin-17,
pubmed-meshheading:14707469-Lymphocyte Activation,
pubmed-meshheading:14707469-Nickel,
pubmed-meshheading:14707469-Receptors, Antigen, T-Cell, alpha-beta,
pubmed-meshheading:14707469-Skin Tests
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pubmed:year |
2003
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pubmed:articleTitle |
Cytokine production, lymphocyte proliferation and T-cell receptor Vbeta expression in primary peripheral blood mononuclear cell cultures from nickel-allergic individuals.
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pubmed:affiliation |
Department of Molecular and Clinical Medicine, Division of Molecular and Immunological Pathology (AIR), Linköping University, Linköping, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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