Source:http://linkedlifedata.com/resource/pubmed/id/14706842
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-3
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pubmed:dateCreated |
2004-1-6
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pubmed:abstractText |
Spermine is the final product of the polyamine biosynthetic pathway and is ubiquitously present in most organisms. The genome of Arabidopsis thaliana has two genes encoding spermine synthase: ACAULIS5 (ACL5), whose loss-of-function mutants show a severe defect in stem elongation, and SPMS. In order to elucidate the function of spermine in plants, we isolated a T-DNA insertion mutant of the SPMS gene. Free and conjugated spermine levels in the mutant, designated spms-1, were significantly decreased compared with those in the wild-type, but no obvious morphological phenotype was observed in spms-1 plants. We further confirmed that acl5-1 spms-1 double mutants contained no spermine. Surprisingly, acl5-1 spms-1 was fully as viable as the wild-type and showed no phenotype except for the reduced stem growth due to acl5-1. These results indicate that spermine is not essential for survival of Arabidopsis, at least under normal growth conditions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Arabidopsis Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Plant,
http://linkedlifedata.com/resource/pubmed/chemical/Polyamines,
http://linkedlifedata.com/resource/pubmed/chemical/RNA,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Spermine,
http://linkedlifedata.com/resource/pubmed/chemical/Spermine Synthase
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0014-5793
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
556
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
148-52
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14706842-Arabidopsis,
pubmed-meshheading:14706842-Arabidopsis Proteins,
pubmed-meshheading:14706842-DNA, Plant,
pubmed-meshheading:14706842-Genes, Plant,
pubmed-meshheading:14706842-Genome, Plant,
pubmed-meshheading:14706842-Mutagenesis, Insertional,
pubmed-meshheading:14706842-Phenotype,
pubmed-meshheading:14706842-Polyamines,
pubmed-meshheading:14706842-RNA,
pubmed-meshheading:14706842-Recombinant Proteins,
pubmed-meshheading:14706842-Seedling,
pubmed-meshheading:14706842-Spermine,
pubmed-meshheading:14706842-Spermine Synthase
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pubmed:year |
2004
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pubmed:articleTitle |
Spermine is not essential for survival of Arabidopsis.
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pubmed:affiliation |
Division of Biological Sciences, Graduate School of Science, Hokkaido University, 060-0810, Sapporo, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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