Linked Life Data

14704953

Source:http://linkedlifedata.com/resource/pubmed/id/14704953

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2004-1-5
pubmed:abstractText
The kinetics of signaling endosome retrograde transport along axons is analyzed and offered as evidence that such transport is more efficient than diffusion or calcium wave-based signaling systems over even relatively small distances. Evidence is provided to support the signaling endosome hypothesis and to expand the hypothesis to include signaling in many cell types and many cellular dimensions. Finally, a saltatory, regenerating inositol 1,4,5-trisphosphate wave model is offered to reconcile current discrepancies in the literature regarding endosomal-based retrograde signaling.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-3034
pubmed:author
pubmed:copyrightInfo
Copyright 2003 Wiley Periodicals, Inc.
pubmed:issnType
Print
pubmed:day
5
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
207-16
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Signaling endosome hypothesis: A cellular mechanism for long distance communication.
pubmed:affiliation
Mechanisms of Neural Repair Lab, Department of Neurology, Mayo Medical and Graduate Schools, Guggenheim 442C, 200 First Street SW, Rochester, Minnesota 55905, USA. howe.charles@mayo.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't