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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
6
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pubmed:dateCreated |
2004-1-5
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|
pubmed:abstractText |
Common variable immunodeficiency (CVID) is a primary defect that is characterized by impaired antibody production. CVID patients may develop recurrent infections, autoimmune disorders and/or systemic granulomatosis. It is well documented that CVID patients are at risk to develop malignant lymphomas. However, to the best of our knowledge, lymphoma complicating the course of CVID associated with systemic granulomatosis has never been reported. We describe two CVID patients with systemic granulomatosis who developed B-cell lymphomas, one related to Epstein Barr virus infection, 5 and 12 yr after CVID had been diagnosed.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0902-4441
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
459-63
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:14703697-B-Lymphocytes,
pubmed-meshheading:14703697-Biopsy,
pubmed-meshheading:14703697-Bone Marrow,
pubmed-meshheading:14703697-Common Variable Immunodeficiency,
pubmed-meshheading:14703697-Diabetes Mellitus, Type 2,
pubmed-meshheading:14703697-Epstein-Barr Virus Infections,
pubmed-meshheading:14703697-Fatal Outcome,
pubmed-meshheading:14703697-Female,
pubmed-meshheading:14703697-Granuloma,
pubmed-meshheading:14703697-Hepatomegaly,
pubmed-meshheading:14703697-Herpesvirus 4, Human,
pubmed-meshheading:14703697-Humans,
pubmed-meshheading:14703697-Liver,
pubmed-meshheading:14703697-Lymph Nodes,
pubmed-meshheading:14703697-Lymphoma, B-Cell,
pubmed-meshheading:14703697-Male,
pubmed-meshheading:14703697-Middle Aged,
pubmed-meshheading:14703697-RNA, Viral,
pubmed-meshheading:14703697-Splenomegaly,
pubmed-meshheading:14703697-T-Lymphocytes
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pubmed:year |
2003
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pubmed:articleTitle |
Lymphoma complicating common variable immunodeficiency with granulomatous disease: report of two cases.
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pubmed:affiliation |
Department of Internal Medicine, Hôpital Avicenne, Assistance Publique-Hôpitaux de Paris and Université Paris-Nord, Bobigny, France.
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pubmed:publicationType |
Journal Article,
Case Reports
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