Linked Life Data

14702757

Source:http://linkedlifedata.com/resource/pubmed/id/14702757

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2004-1-1
pubmed:abstractText
Squamous cell carcinoma of the oral cavity is the sixth most frequent cancer in the world and of the approximately 30,000 new cases diagnosed annually in the United States, 60% occur in males and over 90% of the cases occur in patients over 45 years of age. The overall 5-year survival rate for patients with oral squamous cell carcinoma is among the lowest for major cancers and has not changed during the past two decades. Assessing the risk of oral cancer prior to choosing the therapeutic strategy administered is of paramount importance. Although imperfect but generally available, assays that identify loss of heterozygosity and determine ploidy are an improvement over current ways of assessing the risk of oral cancer. Molecular probing significantly increases the sensitivity and specificity of conventional histopathology. It is now possible to detect a single cancer cell in 10,000 cells. In any case oral cancer remains a disfiguring disease associated with a high mortality rate. Abstinence from smoking and alcohol is the best approach to prevent its occurrence.
pubmed:language
heb
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0017-7768
pubmed:author
pubmed:issnType
Print
pubmed:volume
142
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
862-6, 876
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
[Oral cancer--nuclear acid and genomic aberrations].
pubmed:affiliation
Oral and Maxillofacial Surgery Department, Oral Biochemistry Laboratory, Rambam Medical Center, Faculty of Medicine, Technion, Haifa, Israel.
pubmed:publicationType
Journal Article, English Abstract, Review