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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2003-12-30
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pubmed:abstractText |
Mutations in either adenosine triphosphate- binding cassette (ABC) half-transporter G5 or G8 cause sitosterolemia. It has been proposed that ABCG5/ABCG8 heterodimers mediate secretion of plant sterols and cholesterol by hepatocytes into bile and their efflux from enterocytes into the intestinal lumen.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ABCG5 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters,
http://linkedlifedata.com/resource/pubmed/chemical/Anticholesteremic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Bile Acids and Salts,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Hydrocarbons, Fluorinated,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Orphan Nuclear Receptors,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipids,
http://linkedlifedata.com/resource/pubmed/chemical/Phytosterols,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cytoplasmic and Nuclear,
http://linkedlifedata.com/resource/pubmed/chemical/Sitosterols,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfonamides,
http://linkedlifedata.com/resource/pubmed/chemical/TO-901317,
http://linkedlifedata.com/resource/pubmed/chemical/campesterol,
http://linkedlifedata.com/resource/pubmed/chemical/liver X receptor,
http://linkedlifedata.com/resource/pubmed/chemical/sitosterol
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:BerdySaraS,
pubmed-author:BloksVincent WVW,
pubmed-author:GroenAlbert KAK,
pubmed-author:KemaIdo PIP,
pubmed-author:KuipersFolkertF,
pubmed-author:PlöschTorstenT,
pubmed-author:SchwartzMargritM,
pubmed-author:SchwarzMargritM,
pubmed-author:SieglerKarenK,
pubmed-author:SuhrOleO,
pubmed-author:TerasawaYukoY,
pubmed-author:Van Der SluijsFjodorF
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pubmed:issnType |
Print
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pubmed:volume |
126
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
290-300
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:14699507-ATP-Binding Cassette Transporters,
pubmed-meshheading:14699507-Animals,
pubmed-meshheading:14699507-Anticholesteremic Agents,
pubmed-meshheading:14699507-Bile,
pubmed-meshheading:14699507-Bile Acids and Salts,
pubmed-meshheading:14699507-Cholesterol,
pubmed-meshheading:14699507-DNA-Binding Proteins,
pubmed-meshheading:14699507-Gallbladder,
pubmed-meshheading:14699507-Genotype,
pubmed-meshheading:14699507-Hydrocarbons, Fluorinated,
pubmed-meshheading:14699507-Lipoproteins,
pubmed-meshheading:14699507-Mice,
pubmed-meshheading:14699507-Mice, Knockout,
pubmed-meshheading:14699507-Orphan Nuclear Receptors,
pubmed-meshheading:14699507-Phospholipids,
pubmed-meshheading:14699507-Phytosterols,
pubmed-meshheading:14699507-Receptors, Cytoplasmic and Nuclear,
pubmed-meshheading:14699507-Sitosterols,
pubmed-meshheading:14699507-Sulfonamides
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pubmed:year |
2004
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pubmed:articleTitle |
Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor.
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pubmed:affiliation |
Center for Liver, Digestive and Metabolic Diseases, University Hospital Groningen, Groningen, The Netherlands. t.ploesch@med.rug.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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