Source:http://linkedlifedata.com/resource/pubmed/id/14698479
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2003-12-30
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pubmed:abstractText |
To examine the effects of change in meteorological parameters on pain-related behaviors in a simulated arthritic condition, rats with an injection of complete Freund's adjuvant into the tibio-tarsal joint were exposed to low barometric pressure (20 mmHg below the natural atmospheric pressure) and low ambient temperature (7 degrees C lower than 22 degrees C) in a climate-controlled room. When the arthritic rats were exposed to these environments, the already increased number of hindpaw withdrawals in response to noxious mechanical stimulation (hyperalgesia) was further increased, and a hindpaw withdrawal response to innocuous mechanical stimulation (allodynia) began to occur. Such exposures did not influence any of the pain-related behaviors of the control rats. These results show that lowering barometric pressure and ambient temperature within the range of natural environmental fluctuation intensify pain in arthritic rats.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
354
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
46-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:14698479-Animals,
pubmed-meshheading:14698479-Arthritis, Experimental,
pubmed-meshheading:14698479-Atmospheric Pressure,
pubmed-meshheading:14698479-Cold Temperature,
pubmed-meshheading:14698479-Hyperalgesia,
pubmed-meshheading:14698479-Male,
pubmed-meshheading:14698479-Pain,
pubmed-meshheading:14698479-Pain Measurement,
pubmed-meshheading:14698479-Rats,
pubmed-meshheading:14698479-Rats, Sprague-Dawley,
pubmed-meshheading:14698479-Weather
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pubmed:year |
2004
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pubmed:articleTitle |
Artificially produced meteorological changes aggravate pain in adjuvant-induced arthritic rats.
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pubmed:affiliation |
Department of Neural Regulation, Research Institute of Environmental Medicine, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan. jun@riem.nagoya-u.ac.jp
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pubmed:publicationType |
Journal Article
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