14698165

Source:http://linkedlifedata.com/resource/pubmed/id/14698165

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0205314, umls-concept:C0243077, umls-concept:C0679622, umls-concept:C1335281, umls-concept:C1709439, umls-concept:C1880355
pubmed:issue	2
pubmed:dateCreated	2003-12-30
pubmed:abstractText	A small library of 19 compounds was designed based on unique structural features of PTP1b. Utilizing electrospray ionization mass spectrometry (ESI-MS) to provide binding information about complexes of enzyme and small molecule ligands, two classes of lead compounds were discovered.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Protein Tyrosine Phosphatase..., http://linkedlifedata.com/resource/pubmed/chemical/Protein Tyrosine Phosphatases
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	0960-894X
pubmed:author	pubmed-author:GadekThomas RTR, pubmed-author:OckeyDenise ADA
pubmed:issnType	Print
pubmed:day	19
pubmed:volume	14
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	389-91
pubmed:dateRevised	2007-11-15
pubmed:meshHeading	pubmed-meshheading:14698165-Enzyme Inhibitors, pubmed-meshheading:14698165-Protein Tyrosine Phosphatase, Non-Receptor Type 1, pubmed-meshheading:14698165-Protein Tyrosine Phosphatases, pubmed-meshheading:14698165-Spectrometry, Mass, Electrospray Ionization
pubmed:year	2004
pubmed:articleTitle	Discovery of novel PTP1b inhibitors.
pubmed:affiliation	Genentech, Inc., Department of Bioorganic Chemistry, One DNA Way, South San Francisco, CA 94080, USA. ockey@speakeasy.net
pubmed:publicationType	Journal Article