Source:http://linkedlifedata.com/resource/pubmed/id/14696401
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
54
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| pubmed:dateCreated |
2003-12-30
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| pubmed:abstractText |
The EDG-2 (endothelial cell differentiation gene-2) has been characterized as one of the high-affinity receptors of lysophosphatidic acid: an extracellular lipid mediator which can induce tumor progression. Recent studies have revealed that EDG-2 plays an important role in various pathological events including cell proliferation and tumor development. The investigation of EDG-2 is thus considered important for eliciting the mechanism of tumorigenesis. However, in colorectal tissue, the clinical significance of EDG-2 expression remains unclear. In the current study, we examined the immunohistochemical expression of EDG-2 in colorectal mucosa and adenoma, and clarified its relation with the clinicopathological features.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:issn |
0172-6390
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
50
|
| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
1770-3
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:14696401-Adenocarcinoma,
pubmed-meshheading:14696401-Adenoma,
pubmed-meshheading:14696401-Adenoma, Villous,
pubmed-meshheading:14696401-Adenomatous Polyps,
pubmed-meshheading:14696401-Carcinoma in Situ,
pubmed-meshheading:14696401-Cell Transformation, Neoplastic,
pubmed-meshheading:14696401-Colon,
pubmed-meshheading:14696401-Colonic Polyps,
pubmed-meshheading:14696401-Colorectal Neoplasms,
pubmed-meshheading:14696401-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:14696401-Humans,
pubmed-meshheading:14696401-Immunoenzyme Techniques,
pubmed-meshheading:14696401-Intestinal Mucosa,
pubmed-meshheading:14696401-Prognosis,
pubmed-meshheading:14696401-Receptors, G-Protein-Coupled,
pubmed-meshheading:14696401-Receptors, Lysophosphatidic Acid,
pubmed-meshheading:14696401-Rectum
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| pubmed:articleTitle |
The Immunohistochemical expression of endothelial cell differentiation gene-2 receptor in human colorectal adenomas.
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| pubmed:affiliation |
Department of Surgical Oncology, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. komuro@kt.rim.or.jp
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| pubmed:publicationType |
Journal Article
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