Linked Life Data

14695849

Source:http://linkedlifedata.com/resource/pubmed/id/14695849

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2003-12-29
pubmed:abstractText
The treatment of adults with acute lymphoblastic leukemia (ALL) has been modeled on therapy developed for childhood ALL. The similarity between childhood and adult forms of this disease allows for inferences to be drawn from experience in the pediatric population. However, adults with ALL have far poorer outcome when compared to children. Some of this difference can be attributed in ability to tolerate intensive therapy coupled with an increased incidence of unfavorable cytogenetic subgroups and a decreased incidence of favorable cytogenetic subgroups. Treatment of adult ALL is typically divided into four broad categories: induction, consolidation, maintenance, and central nervous system prophylaxis. Despite three decades of clinical investigation for devising improved treatment programs for adults with ALL, no single program has emerged as the standard. Here we review classification, prognostic features, current treatment programs, and new advances as applied to adult patients with newly diagnosed ALL.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1540-3408
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
40-6
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Treatment options for newly diagnosed patients with adult acute lymphoblastic leukemia.
pubmed:affiliation
Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10022, USA.
pubmed:publicationType
Journal Article, Review